Albrahim Tarfa Ibrahim, Binobead Manal Abdulaziz
Department of Health Sciences, College of Health and Rehabilitation Sciences. Princess Nourah bint Abdulrahman University.
Food Science and Nutrition Department, College of Food Science and Agriculture, King Saud University, Riyadh, Saudi Arabia.
Saudi Pharm J. 2019 Feb;27(2):200-207. doi: 10.1016/j.jsps.2018.10.004. Epub 2018 Oct 17.
The aim of the present study was to evaluate the association between Bone mineral density in lumber spine and femoral neck with serum total levels of vitamin D, sun exposure and Consumption of vitamin D Supplement in obese Saudi females aged between 30 and 54 years old. Recent attention to the high prevalence of osteoporosis and its association with low vitamin D levels in adults has raised the importance of vitamin D evaluation. A low level of vitamin D is considered to be one of the most important risk factors for osteoporosis. In this study; 120 obese Saudi females with no diagnosed chronic diseases attending the Outpatient clinic at king Khalid University hospital in Riyadh. Saudi Arabia, recruited randomly in period of 12 months. In this study, Serum levels of total Vitamin D were considered to be severe deficient if it was lower than 25 ng/mL, mild to moderate deficient if it was between 25 and 60 ng/mL and optimum level if it was 61-200 ng/mL. The results showed that; sun exposure was significantly affect and Correlate with serum level of Vitamin D in the subjects. In addition, daily consumption of Vitamin D supplement was significantly affect and Correlate with serum level of Vitamin D in the subjects of this study. Moreover, the results showed that; 50% of the age group (40-49 years old) having severe deficiency of Vitamin D. While, 50% of the age group (50-59 years old) having optimal level of Vitamin D. And these results mean that age is not Correlated with vitamin D deficiency in subjects of this study.
本研究的目的是评估年龄在30至54岁之间的肥胖沙特女性腰椎和股骨颈骨矿物质密度与血清维生素D总水平、阳光照射及维生素D补充剂摄入量之间的关联。近期对骨质疏松症高患病率及其与成年人低维生素D水平关联的关注提高了维生素D评估的重要性。低维生素D水平被认为是骨质疏松症最重要的危险因素之一。在本研究中，120名未被诊断患有慢性病的肥胖沙特女性在利雅得的哈立德国王大学医院门诊就诊。在12个月期间随机招募。在本研究中，如果血清总维生素D水平低于25 ng/mL，则被认为严重缺乏；如果在25至60 ng/mL之间，则为轻度至中度缺乏；如果为61 - 200 ng/mL，则为最佳水平。结果显示，阳光照射对受试者血清维生素D水平有显著影响且与之相关。此外，每日服用维生素D补充剂对本研究受试者血清维生素D水平也有显著影响且与之相关。而且，结果显示，年龄组中50%（40 - 49岁）的人维生素D严重缺乏。而年龄组中50%（50 - 59岁）的人维生素D水平最佳。这些结果意味着在本研究受试者中年龄与维生素D缺乏无关。
