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锌缺乏对大鼠视网膜发育中光感受器的影响:一项扫描显微镜研究。

The effects of zinc deficiency on developing photoreceptors in the rat retina: a scanning microscopic study.

作者信息

Sinning A R, Olson M D, Sandstead H H

出版信息

Scan Electron Microsc. 1984(Pt 2):867-73.

PMID:6484502
Abstract

A study was undertaken to observe the effects of dietary zinc deficiency on the topographical morphology of developing photoreceptor (rod) cells in the sensory retina of the rat. Observations were made by means of scanning electron microscopy (SEM). Pups were utilized from three groups including (1) zinc deficient (2) pair-fed controls and (3) ad libitum controls. Animals ranged in age from birth to twenty days. Femur zinc levels were measured by flame atomic absorption spectrophotometry. A statistically significant increase in the number of photoreceptor cells continued through the 6th day, however, no morphological differences were noted among cells during the first 13 days. By day 14, outer segments appeared more elongated in ad libitum control tissues. No differences in outer segment length were apparent by day 20.

摘要

进行了一项研究,以观察饮食中锌缺乏对大鼠感觉视网膜中发育中的光感受器(视杆)细胞的地形形态的影响。通过扫描电子显微镜(SEM)进行观察。使用了来自三组的幼崽,包括(1)缺锌组(2)配对喂养对照组和(3)自由采食对照组。动物年龄从出生到二十天不等。通过火焰原子吸收分光光度法测量股骨锌水平。光感受器细胞数量在第6天之前持续有统计学意义的增加,然而,在最初的13天内细胞之间未观察到形态学差异。到第14天,自由采食对照组织中的外段显得更长。到第20天,外段长度没有明显差异。

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