Rovan E, Kalla N R, Frick J, Adam H
Urol Res. 1984;12(3):187-92. doi: 10.1007/BF00255921.
Gossypol acetic acid in a concentration of 1,000 microgram/ml solvent is able to immobilize 1 ml of native bull semen (sperm concentration: 8.5 X 10(8)/ml; motility rate: 87.4%) within 30 min. After GAA treatment the spermatozoa show severe morphological damage on the membrane system, on the acrosomal complex and on the tubular complex of the end piece. The working mechanism of GAA can be assumed to be inactivation of enzyme activities or in direct reactions with plasma membrane material.
浓度为1000微克/毫升溶剂的醋酸棉酚能够在30分钟内使1毫升天然公牛精液（精子浓度：8.5×10⁸/毫升；活力率：87.4%）失去活性。经醋酸棉酚处理后，精子在膜系统、顶体复合体和尾段的管状复合体上表现出严重的形态损伤。可以认为醋酸棉酚的作用机制是酶活性失活或与质膜物质发生直接反应。
