Warshaw A L, Cambria R P
Ann Surg. 1984 Nov;200(5):595-9. doi: 10.1097/00000658-198411000-00007.
Eight patients with recurrent acute pancreatitis were found by ERCP to have foreshortening of the duct of Wirsung simulating the radiographic appearance of the congenital anomaly pancreas divisum. In contrast to 44 patients with true pancreas divisum, who were predominantly young (mean 32 years), nonalcoholic (42/44), and female (34/44), patients with false pancreas divisum were older (mean 48 years), male (7/8), and alcoholic (5/8). False pancreas divisum is most often an acquired obstructing lesion resulting from irremediable injury to the pancreatic duct during acute pancreatitis, often associated with pseudocyst formation and subsequent healing by scar at the site of duct injury. Appreciation of the radiographic differences between pancreatograms in true and false pancreas divisum and the different findings at operation allow for proper selection of therapy. Whereas accessory papilla sphincteroplasty appears to be effective for recurrent pancreatitis associated with true pancreas divisum, false pancreas divisum requires distal pancreatectomy or pancreaticojejunostomy to overcome the irreversible obstruction of the main pancreatic duct.
经内镜逆行胰胆管造影(ERCP)发现,8例复发性急性胰腺炎患者存在主胰管缩短,其影像学表现类似先天性胰腺分裂畸形。与44例真性胰腺分裂患者不同,真性胰腺分裂患者以年轻人为主(平均32岁),非酒精性(42/44),女性居多(34/44),假性胰腺分裂患者年龄较大(平均48岁),男性居多(7/8),且多为酒精性(5/8)。假性胰腺分裂通常是一种后天性梗阻性病变,由急性胰腺炎期间胰管不可修复的损伤所致,常伴有假性囊肿形成,随后在导管损伤部位通过瘢痕愈合。认识到真性和假性胰腺分裂的胰胆管造影影像学差异以及手术中的不同发现,有助于正确选择治疗方法。对于与真性胰腺分裂相关的复发性胰腺炎,副乳头括约肌成形术似乎有效,而假性胰腺分裂则需要进行胰体尾切除术或胰管空肠吻合术,以克服主胰管的不可逆梗阻。