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锂盐和苯丙胺配对味道在多次条件反射/测试试验中引发的行为条件反应。

Behavioral conditioned responses across multiple conditioning/testing trials elicited by lithium- and amphetamine-paired flavors.

作者信息

Parker L A

出版信息

Behav Neural Biol. 1984 Jul;41(2):190-9. doi: 10.1016/s0163-1047(84)90569-7.

DOI:10.1016/s0163-1047(84)90569-7
PMID:6487218
Abstract

The present experiment measured the pattern of conditioned responses across 10 conditioning/testing trials which were elicited by an intraoral presentation of either a lithium- or an amphetamine-paired flavor. A nonspecific conditioned response pattern of suppressed limb flicking after five conditioning trials and of suppressed scratching after six conditioning trials was supported by both drugs. Lithium-specific increased activity level after one conditioning trial and chin rubbing after two conditioning trials were observed across conditioning/testing days. The lithium-specific conditioned responses were not the result of a stronger flavor aversion, because both lithium and amphetamine produced equivalent flavor avoidance responses across the 10 conditioning/testing trials. The results support previous research which suggests that flavor aversions produced by lithium and amphetamine are produced by different unconditioned response mechanisms.

摘要

本实验测量了在10次条件反射/测试试验中,由口腔内呈现与锂盐或苯丙胺配对的味道所引发的条件反应模式。两种药物均支持一种非特异性的条件反应模式,即在5次条件反射试验后出现抑制性肢体轻弹,在6次条件反射试验后出现抑制性抓挠。在整个条件反射/测试期间,观察到锂盐特异性的现象,即在1次条件反射试验后活动水平增加,在2次条件反射试验后出现颏摩擦。锂盐特异性的条件反应并非更强的味道厌恶的结果,因为在10次条件反射/测试试验中,锂盐和苯丙胺产生的味道回避反应相当。这些结果支持了先前的研究,该研究表明锂盐和苯丙胺产生的味道厌恶是由不同的非条件反应机制引起的。

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