Eschalier A, Lavarenne J, Renoux M
Cancer Chemother Pharmacol. 1984;13(3):240-1. doi: 10.1007/BF00269039.
The bronchoconstrictor effect of elliptinium already demonstrated in the guinea-pig is shown in the dog. It is less intense and its onset is prompter. Successive administration of identical doses of elliptinium attenuates the bronchospasm induced, suggesting tachyphylaxis. The previously described indirect bronchoconstrictor effect involving endogenous mediators seems also to be active in these circumstances.
已在豚鼠身上得到证实的椭圆玫瑰树碱的支气管收缩效应在犬身上也有体现。其效应较弱，但起效更快。连续给予相同剂量的椭圆玫瑰树碱会减轻所诱发的支气管痉挛，提示速发性耐受性。先前描述的涉及内源性介质的间接支气管收缩效应在这些情况下似乎也起作用。
