DiSessa T G, Child J S, Perloff J K, Wu L, Williams R G, Laks H, Friedman W F
Circulation. 1984 Nov;70(5):898-902. doi: 10.1161/01.cir.70.5.898.
Despite increasing use of Fontan or modified Fontan repairs, the comparative hemodynamic efficacy of different types of connections are unresolved. Accordingly, we undertook a prospective study designed to determine postoperative flow patterns after Fontan's operation. Seven subjects had tricuspid atresia and eight had single ventricle. Ages ranged from 5 to 38 years (mean 16.4). Ten subjects had nonvalved right atrial-to-pulmonary arterial connection, and four had nonvalved right atrial-to-right ventricular communication. A valved conduit established continuity between the right atrium and right ventricle in one subject. Doppler flow profiles were recorded in the pulmonary artery and in the superior and inferior venae cavae of each. A reference electrocardiogram was used for timing purposes. In 14 patients, forward flow in the pulmonary artery was biphasic. Flow began at the end of the T wave (early ventricular diastole), peaked at or before the P wave (atrial systole), and returned to baseline by the peak of the R wave. Forward flow recommenced at the peak of the R wave (ventricular systole) and returned to baseline at the end of the T wave. Flow in the superior vena cava varied, and could not be recorded in three subjects. Between the end of the P wave and peak of the R wave (atrial systole) flow was reversed in eight, absent in three, and forward in one patient. Forward flow occurred between the peak of the R wave and the end of the T wave and was either continuous or biphasic. Fourteen patients had adequate studies of inferior vena cava flow; reversed flow during atrial systole occurred in 10 subjects.(ABSTRACT TRUNCATED AT 250 WORDS)
尽管Fontan手术或改良Fontan手术的应用越来越多,但不同类型连接方式的相对血流动力学效果仍未明确。因此,我们进行了一项前瞻性研究,旨在确定Fontan手术后的血流模式。7名受试者患有三尖瓣闭锁,8名患有单心室。年龄范围为5至38岁(平均16.4岁)。10名受试者采用无瓣右心房至肺动脉连接,4名采用无瓣右心房至右心室连通。1名受试者通过带瓣管道建立右心房与右心室之间的连续性。记录了每位受试者肺动脉以及上、下腔静脉的多普勒血流频谱。使用参考心电图进行计时。14例患者肺动脉前向血流呈双相。血流始于T波末(心室舒张早期),在P波处或之前达到峰值(心房收缩期),并在R波峰值时回到基线。前向血流在R波峰值(心室收缩期)再次开始,并在T波末回到基线。上腔静脉血流各异,3名受试者无法记录。在P波末至R波峰值(心房收缩期)之间,8例患者血流反向,3例缺失,1例前向。前向血流发生在R波峰值至T波末之间,呈连续或双相。14例患者对下腔静脉血流进行了充分研究;10名受试者在心房收缩期出现反向血流。(摘要截选至250字)