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Fontan手术后患者右心血流动力学

Dynamics of right heart flow in patients after Fontan procedure.

作者信息

Nakazawa M, Nakanishi T, Okuda H, Satomi G, Nakae S, Imai Y, Takao A

出版信息

Circulation. 1984 Feb;69(2):306-12. doi: 10.1161/01.cir.69.2.306.

Abstract

In seven patients who underwent Fontan procedures but in whom no valves were inserted, dynamics of right heart flow were evaluated with the use of a catheter-tipped velocity transducer, pulsed Doppler echocardiography, and angiocardiography. Right atrial (RA) contraction caused a forward flow to the pulmonary artery (PA) and a backward flow to the inferior vena cava (IVC). Backward flow to the superior vena cava (SVC) was minimal. As the right atrium relaxed, a rapid forward flow occurred at the IVC and SVC that filled the atrium and a small amount of pulmonary regurgitant flow was observed. Subsequently, a forward flow was observed at the IVC, SVC, and PA during RA diastole. Angiographically determined RA stroke volume (SV) was less than 40% of the left ventricular (LV) SV in three patients in whom the postoperative increase in atrial "a" wave pressure (delta p) was greater than 8 mm Hg, while it was similar to or greater than LVSV in four patients in whom delta p was 6 mm Hg or less. In all patients LV end-diastolic volume was 107 +/- 27(SD)% of normal but LV ejection fraction was 0.53 +/- 0.07, resulting in the reduced cardiac output (2.8 +/- 0.7 l/min/m2). There was no correlation between the RASV or RA ejection fraction and cardiac output. These data show that the RA contraction causes a forward flow to the PA and that pulmonary regurgitation is not significant after Fontan procedure even when valves are not inserted. Also, the postoperative increase in the RA afterload may depress RA function.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在7例接受Fontan手术但未植入瓣膜的患者中,使用导管顶端速度换能器、脉冲多普勒超声心动图和心血管造影术评估右心血流动力学。右心房(RA)收缩导致肺动脉(PA)出现前向血流,下腔静脉(IVC)出现逆向血流。上腔静脉(SVC)的逆向血流最小。随着右心房舒张,IVC和SVC出现快速前向血流,充盈心房,并观察到少量肺反流。随后,在RA舒张期,IVC、SVC和PA均观察到前向血流。在术后心房“a”波压力升高(δp)大于8 mmHg的3例患者中,血管造影测定的RA每搏量(SV)小于左心室(LV)SV的40%,而在δp为6 mmHg或更低的4例患者中,RA SV与LV SV相似或更大。所有患者的LV舒张末期容积为正常的107±27(SD)%,但LV射血分数为0.53±0.07,导致心输出量降低(2.8±0.7 l/min/m2)。RASV或RA射血分数与心输出量之间无相关性。这些数据表明,RA收缩导致PA出现前向血流,并且即使未植入瓣膜,Fontan手术后肺反流也不显著。此外,术后RA后负荷增加可能会抑制RA功能。(摘要截断于250字)

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