Eble J N, Hull M T
Hum Pathol. 1984 Nov;15(11):1054-61. doi: 10.1016/s0046-8177(84)80249-x.
Five renal oncocytomas were studied by light and electron microscopy. Five glutaraldehyde-fixed blocks from each tumor were examined. Scarce short, blunt microvilli, plasmalemmal interdigitations, basement membrane protuberances, and round or oval mitochondrial profiles were found, suggesting that these neoplasms arise from the epithelium of the distal tubule. Morphologic criteria for the diagnosis of renal oncocytoma, including ultrastructural demonstration of cytoplasmic filling by mitochondria, are presented.
对5例肾嗜酸细胞瘤进行了光镜和电镜研究。对每个肿瘤的5个经戊二醛固定的组织块进行了检查。发现有稀少的短而钝的微绒毛、质膜指状突、基底膜突起以及圆形或椭圆形的线粒体轮廓,提示这些肿瘤起源于远端小管上皮。本文提出了肾嗜酸细胞瘤的诊断形态学标准,包括线粒体充满细胞质的超微结构表现。