Surrenti C, Salvadori G, Casini A, Nieri S, Ricci O E, Ceccatelli P, Parenti S, Patussi V, Gentilini P
Int J Clin Pharmacol Ther Toxicol. 1984 Aug;22(8):435-7.
A group of 41 patients (25 males and 16 females) with mild chronic active hepatitis was studied for a mean follow-up period of 6.5 years. All patients had liver biopsy on admission and a second biopsy during the follow-up period. All but 7 patients were treated with prednisolone. Most of the patients were asymptomatic. There was no history of alcohol abuse or chronic administration of drugs. Fourteen patients were HBsAg positive and 27 HBsAg negative. Circulating autoantibodies were absent. Thirty-three patients did not demonstrate any change in disease activity. Four developed liver cirrhosis and four were apparently cured.
对一组41例轻度慢性活动性肝炎患者（25例男性和16例女性）进行了平均6.5年的随访研究。所有患者入院时均进行了肝活检，并在随访期间进行了第二次活检。除7例患者外，所有患者均接受泼尼松龙治疗。大多数患者无症状。无酗酒或长期用药史。14例患者HBsAg阳性，27例患者HBsAg阴性。未检测到循环自身抗体。33例患者疾病活动度无变化。4例发展为肝硬化，4例明显治愈。
