Walden J, Lehmenkühler A, Speckmann E J, Witte O W
J Neurosci Methods. 1984 Aug;11(3):187-92. doi: 10.1016/0165-0270(84)90037-2.
A double-barrelled microelectrode is described, which permits the continuous measurement of the concentration of the epileptogenic agent pentylenetetrazol (PTZ). The electrode is based on the liquid potassium exchanger (Corning No. 477 317) and enables measurements of PTZ concentration in physiological salines down to 1 mM. The electromotive behaviour of the liquid membrane against PTZ cannot directly be described by the Nicolsky-Eisenman formalism. It is suggested that specific interactions of the PTZ molecule with the Corning ligand are involved in the potential generating mechanisms.
本文描述了一种双管微电极，它能够连续测量致癫痫剂戊四氮（PTZ）的浓度。该电极基于液体钾离子交换剂（康宁477 317号），能够测量生理盐水中低至1 mM的PTZ浓度。液膜对PTZ的电动势行为不能直接用尼科尔斯基-艾森曼公式来描述。有人认为，PTZ分子与康宁配体的特定相互作用参与了电位产生机制。
