速溶咖啡对中国仓鼠肺细胞培养物的致突变性。
Mutagenicity of instant coffee on cultured Chinese hamster lung cells.
作者信息
Nakasato F, Nakayasu M, Fujita Y, Nagao M, Terada M, Sugimura T
出版信息
Mutat Res. 1984 Oct;141(2):109-12. doi: 10.1016/0165-7992(84)90020-4.
PMID:6493267
Abstract
Coffee showed mutagenic activity in cultured Chinese hamster lung (CHL) cells as assessed by using diphtheria toxin resistance as a selective marker. Most of the mutagenicity was suppressed in the presence of sodium bisulfite. The contribution of methylglyoxal to the total mutagenicity of coffee was less than 3%.
摘要
以对白喉毒素的抗性作为选择标记进行评估时，咖啡在培养的中国仓鼠肺（CHL）细胞中显示出诱变活性。在亚硫酸氢钠存在的情况下，大部分诱变活性受到抑制。甲基乙二醛对咖啡总诱变活性的贡献小于3%。
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