Labeeuw M, Pozet N, Gerbaulet C, Zech P, Traeger J
Nephrologie. 1984;5(3):101-5.
In calcium stone formers, the ratio of urinary magnesium concentration to urinary calcium concentration (Mg/Ca) is used to express the already reported low Mg excretion relatively to Ca excretion. However the Mg/Ca value depends on the Ca excretion rate, decreases after oral Ca load and is not directly related to Mg excretion. Therefore when studying patients with different Ca excretion rates, or when performing an oral Ca load, Mg/Ca is not directly useful to express a relative hypomagnesuria. We established a new parameter from the normal relationship between urinary Mg and Ca excretion rates. Its value is above - .065 in 97.5% of 99 control urinary samples. It is stable for any studied Ca excretion rate, including post Ca load excretion rates, and is highly correlated with Mg excretion rate. This parameter allows for the accurate diagnosis of relative hypomagnesuria in stone formers.
在钙结石形成者中，尿镁浓度与尿钙浓度之比（Mg/Ca）用于表示相对于钙排泄而言已报道的低镁排泄情况。然而，Mg/Ca值取决于钙排泄率，口服钙负荷后会降低，且与镁排泄无直接关系。因此，在研究不同钙排泄率的患者时，或进行口服钙负荷时，Mg/Ca不能直接用于表示相对低镁尿症。我们根据尿镁与钙排泄率之间的正常关系建立了一个新参数。在99份对照尿样中，97.5%的样本其值高于-.065。对于任何研究的钙排泄率，包括钙负荷后的排泄率，该参数都很稳定，且与镁排泄率高度相关。这个参数能够准确诊断结石形成者中的相对低镁尿症。
