Hargrove C B, Ulshen M H, Shub M D
Pediatrics. 1984 Nov;74(5):828-31.
Although fiberoptic, upper gastrointestinal (UGI) endoscopy has become an accepted diagnostic technique in the older child and adult, concerns about safety have limited the use of this procedure in infants. A 1-year experience with 49 upper gastrointestinal endoscopies in infants less than 25 months of age is reported. There were varied indications for the procedures, including upper gastrointestinal hemorrhage and obstruction, but evaluation for esophagitis secondary to gastroesophageal reflux was most common. Procedures were performed without sedation in 45% of all infants studied, including 87% of infants less than 3 months of age; procedures were well tolerated. General anesthesia was used on only three occasions. A thorough examination was always possible, and biopsies were taken whenever indicated. Only one complication, transient bradycardia, occurred in a critically ill infant. This experience demonstrates that upper gastrointestinal endoscopy is a safe and effective diagnostic aid in infants, and it can often be performed with little or no sedation.
尽管纤维光学上消化道（UGI）内镜检查在大龄儿童和成人中已成为一种被认可的诊断技术，但对安全性的担忧限制了该检查在婴儿中的应用。本文报告了对年龄小于25个月的婴儿进行49例上消化道内镜检查的1年经验。检查的适应证多种多样，包括上消化道出血和梗阻，但因胃食管反流继发食管炎而进行评估最为常见。在所有接受研究的婴儿中，45%的检查未使用镇静剂，其中年龄小于3个月的婴儿有87%未使用镇静剂；检查耐受性良好。仅3次使用了全身麻醉。始终能够进行全面检查，并在有指征时进行活检。仅1例重症婴儿出现了短暂性心动过缓这一并发症。该经验表明，上消化道内镜检查在婴儿中是一种安全有效的诊断辅助手段，并且通常可以在很少或不使用镇静剂的情况下进行。
