Sharma S C, Hoon R S, Balasubramanian V, Chadha K S
J Appl Physiol Respir Environ Exerc Physiol. 1978 May;44(5):725-7. doi: 10.1152/jappl.1978.44.5.725.
Urinary catecholamine excretion was estimated in 50 lowlanders temporarily staying at altitudes above 3,000 m. They were divided in subgroups according to the length of their continuous stay. For comparison, 25 highlanders who were born and brought up at high altitude and 50 lowlanders who had never been to altitudes of more than 1,000 m were also studied. High catecholamine excretion was noted in temporary residents staying at high altitude for up to 30 days as compared to that in lowlanders (P greater than 0.01). The excretion rate gradually returned to basal values thereafter. Catecholamines were essentially similar in lowlanders and highlanders. The significance of these findings is discussed regarding the possible pathogenetic role of the sympathoadrenal system in the development of ill effects in respone to high-altitude exposure.
对50名暂时居住在海拔3000米以上的低地居民的尿儿茶酚胺排泄量进行了估算。根据他们连续停留的时间将他们分成亚组。为作比较，还对25名在高海拔地区出生并长大的高地居民以及50名从未去过海拔超过1000米地区的低地居民进行了研究。与低地居民相比，在高海拔地区停留长达30天的临时居民中观察到儿茶酚胺排泄量较高（P>0.01）。此后排泄率逐渐恢复到基础值。低地居民和高地居民的儿茶酚胺基本相似。就交感肾上腺系统在对高海拔暴露产生不良反应的发展过程中可能的致病作用，对这些发现的意义进行了讨论。
