Lye C R, Downs A R
Can J Surg. 1980 Nov;23(6):536-40.
Over a 15-year period, 161 patients underwent 186 carotid endarterectomies. Of these patients, 97% had symptoms preoperatively. The incidence of new neurologic deficits appearing immediately postoperatively was 7% (13 of 186), and 1.6% (3 of 186) were major permanent strokes. Nineteen patients were lost to follow-up. The cumulative patient survival was 83% at 5 years and 59% at 10 years. The cause of death in the late postoperative period was ascertained in 22 of 24 patients; it was related to ischemic cardiac disease in 16. There were no late deaths from neurologic complications. New or recurrent neurologic symptoms developed in the late postoperative period in 22 patients. There were no disabling strokes in this group. The cumulative rate of freedom from new neurologic symptoms was 82% at 5 years and 71% at 10 years. Repeat angiography was carried out in 12 patients who had new or recurrent neurologic symptoms in the late postoperative period. The repaired artery was found to be widely patent in nine, stenosed in one and occluded in two. Reoperation of the same carotid was not performed in this series. Routine intraoperative angiography aided the detection and correction of potential technical problems.
在15年期间,161例患者接受了186次颈动脉内膜切除术。这些患者中,97%术前有症状。术后即刻出现新的神经功能缺损的发生率为7%(186例中的13例),严重永久性卒中为1.6%(186例中的3例)。19例患者失访。5年时累积患者生存率为83%,10年时为59%。24例患者中有22例确定了术后晚期的死亡原因;其中16例与缺血性心脏病有关。没有因神经并发症导致的晚期死亡。22例患者在术后晚期出现新的或复发的神经症状。该组中没有致残性卒中。5年时无新神经症状的累积发生率为82%,10年时为71%。对12例术后晚期出现新的或复发神经症状的患者进行了重复血管造影。发现修复的动脉9例广泛通畅,1例狭窄,2例闭塞。本系列未对同一颈动脉进行再次手术。术中常规血管造影有助于发现和纠正潜在的技术问题。