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术前肾梗死术后肾细胞癌的体外生长

In vitro growth of renal cell carcinoma after preoperative renal infarction.

作者信息

Bailey G A, Belis J A, Kandzari S J, McClung J E, Horton J A

出版信息

Urology. 1984 Nov;24(5):456-8. doi: 10.1016/0090-4295(84)90321-2.

DOI:10.1016/0090-4295(84)90321-2
PMID:6495455
Abstract

Renal cell carcinoma tissue was cultured from 2 patients who underwent embolization of the tumor before surgery and from 2 patients who did not have the tumor embolized. A combination of small Gelfoam particles and polyvinyl alcohol foam particles (250-590 mu diameter) was used to devascularize maximally the tumors that were embolized. The tumor cells from all 4 patients grew in short-term tissue cultures and demonstrated histology and growth properties characteristic of tumor cells. Successful embolization of renal cell carcinomas may not completely infarct the primary tumor, and local tumor growth may continue.

摘要

从2例术前接受肿瘤栓塞的患者以及2例未进行肿瘤栓塞的患者身上获取肾细胞癌组织进行培养。使用小的明胶海绵颗粒和聚乙烯醇泡沫颗粒(直径250 - 590微米)的组合,对接受栓塞的肿瘤进行最大限度的去血管化处理。来自所有4例患者的肿瘤细胞在短期组织培养中生长,并表现出肿瘤细胞特有的组织学和生长特性。肾细胞癌的成功栓塞可能不会使原发肿瘤完全梗死,局部肿瘤可能会继续生长。

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