Lorentzon R, Larsson H O, Boquist L
Acta Pathol Microbiol Immunol Scand A. 1984 Jul;92(4):257-65. doi: 10.1111/j.1699-0463.1984.tb04402.x.
The parathyroid glands of the normal Mongolian gerbil were studied by light and electron microscopy, using stereology and semi-automatic image analysis. Basic quantitative data are presented for various nuclear parameters, and for mitochondria, endoplasmic reticulum, Golgi complex, secretory granules, storage granules, lysosomes and lipoid bodies. Chief cells predominate in the normal gland. Atrophic cells are only rarely encountered. The chief cells can be qualitatively subclassified into light, dark and intermediate variants, but quantitatively there is no difference among these variants with regard to the volume densities of mitochondria, lamellar rough endoplasmic reticulum, Golgi complex, secretory granules and storage granules, suggesting that the subclassification of the chief cells plays no functional role. A statistically significant correlation between volume densities of Golgi complex and secretory granules was found. Compared with the chief cells, the atrophic cells exhibit significantly less lamellar rough endoplasmic reticulum and secretory granules, whereas the content of vesicular rough endoplasmic reticulum is increased. The atrophic cells are suggested to be a degenerative variant of the chief cells.
利用体视学和半自动图像分析技术，通过光学显微镜和电子显微镜对正常蒙古沙鼠的甲状旁腺进行了研究。给出了各种核参数以及线粒体、内质网、高尔基体、分泌颗粒、储存颗粒、溶酶体和脂质体的基本定量数据。正常腺体中主细胞占主导地位。萎缩细胞很少见。主细胞在性质上可细分为亮细胞、暗细胞和中间型细胞，但在这些细胞类型中，线粒体、板层状粗面内质网、高尔基体、分泌颗粒和储存颗粒的体积密度在数量上没有差异，这表明主细胞的细分没有功能作用。发现高尔基体和分泌颗粒的体积密度之间存在统计学上的显著相关性。与主细胞相比，萎缩细胞的板层状粗面内质网和分泌颗粒明显较少，而泡状粗面内质网的含量增加。萎缩细胞被认为是主细胞的一种退行性变体。
