Shimodori S, Takeya K, Takade A
Am J Epidemiol. 1984 Nov;120(5):759-68. doi: 10.1093/oxfordjournals.aje.a113944.
Attention has recently been given to the increasingly frequent detection of atypical Vibrio cholerae O-1 in the natural environments throughout the world. Lysogenicity of V. cholerae O-1, mainly isolated from environmental sources in nine areas, including the United States, was studied by electron microscopy and a cross-lysis test between bacteria and the culture supernatants. A total of 38 strains isolated in Texas in 1973 and in Louisiana in 1978 were lysogenic, whereas there were no lysogenic strains among those isolated in Louisiana in 1979. Because these phages were identical in terms of serology and host range, the phage in them was named T-L phage. T-L phage differed in host range from the k type phage in the epidemic strain of the seventh cholera pandemic. Although the T-L phage was neutralized by antiserum to the k type phage and vice versa, the two phage types were not serologically identical. By a prophage typing method, strains of V. cholerae O-1 isolated from the environment in Guam, Bangladesh, and Japan were classified as either of the Celebes type (epidemic strain) or the Classic-Ubon type. All strains isolated in Brazil, the Chesapeake Bay, and England were nonlysogenic and classified as Classic-Ubon type.
最近，世界各地自然环境中越来越频繁地检测到非典型霍乱弧菌O-1，这一情况已受到关注。通过电子显微镜以及细菌与培养上清液之间的交叉裂解试验，对主要从包括美国在内的九个地区的环境来源分离出的霍乱弧菌O-1的溶原性进行了研究。1973年在得克萨斯州和1978年在路易斯安那州分离出的总共38株菌株具有溶原性，而1979年在路易斯安那州分离出的菌株中没有溶原性菌株。由于这些噬菌体在血清学和宿主范围方面相同，因此其中的噬菌体被命名为T-L噬菌体。T-L噬菌体在宿主范围上与第七次霍乱大流行流行菌株中的k型噬菌体不同。尽管T-L噬菌体可被抗k型噬菌体血清中和，反之亦然，但这两种噬菌体类型在血清学上并不相同。通过原噬菌体分型方法，从关岛、孟加拉国和日本环境中分离出的霍乱弧菌O-1菌株被分类为西里伯斯型（流行菌株）或经典乌汶型。在巴西、切萨皮克湾和英国分离出的所有菌株均无溶原性，被分类为经典乌汶型。
