Pearce R S, West L R, Rodeheaver G T, Edlich R F
Am J Surg. 1984 Nov;148(5):687-91. doi: 10.1016/0002-9610(84)90351-9.
The performance of silicone drains has been improved by coating their surfaces with a hydrogel polymer. This hydrogel is formed by reacting polyvinylpyrrolidone with an isocyanate prepolymer. By absorbing water, the hydrogel creates a drain surface with a low coefficient of friction. The results of this experimental study demonstrate that the surface coating reduces the adherence of blood clots to the drain and facilitates its removal from the wound. On the basis of these and other experiments, the Food and Drug Administration has allowed the use of hydrogel for coating surgical drains for use in patients.
通过用水凝胶聚合物涂覆硅胶引流管的表面，其性能得到了改善。这种水凝胶是由聚乙烯吡咯烷酮与异氰酸酯预聚物反应形成的。通过吸收水分，水凝胶形成了一个摩擦系数低的引流管表面。这项实验研究的结果表明，表面涂层减少了血凝块对引流管的附着，并便于将其从伤口移除。基于这些及其他实验，美国食品药品监督管理局已允许将水凝胶用于涂覆供患者使用的手术引流管。
