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[采用肌内注射长效睾酮对先天性阴茎发育不全进行早期治疗]

[Early treatment of congenital hypoplasia of the penis with intramuscular delayed-action testosterone].

作者信息

Landier F, Chaussain J L, Job J C

出版信息

Arch Fr Pediatr. 1984 Aug-Sep;41(7):467-71.

PMID:6497554
Abstract

Three intramuscular injections of 25 to 50 mg of testosterone hexahydrobenzoate were prescribed in 37 boys who presented with hypoplastic penis: 16 with micropenis and normally placed urethra, 21 with hypospadias. Ages ranged from 4 months to 9 years. In almost all children treated between the ages of 6 and 18 months, penis growth became normal for age. Growth and bone maturation were temporarily accelerated but in a parallel fashion, so that this very early androgen-therapy need not reduce the adult height of children thus treated.

摘要

对37名阴茎发育不全的男孩,处方给予三次肌肉注射25至50毫克的己酸睾酮:16名患有小阴茎且尿道位置正常,21名患有尿道下裂。年龄范围从4个月至9岁。在几乎所有6至18个月接受治疗的儿童中,阴茎生长达到了与其年龄相符的正常水平。生长和骨骼成熟暂时加速,但呈平行方式,因此这种极早期的雄激素治疗不一定会降低接受治疗儿童的成年身高。

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Childhood growth in boys with congenital hypogonadotropic hypogonadism.先天性低促性腺激素性性腺功能减退男孩的儿童期生长情况
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