Vanelli M, Bernasconi S, Terzi C, Bolondi O, Boselli E, Virdis R, Giovannelli G
Arch Fr Pediatr. 1984 Aug-Sep;41(7):473-6.
Two groups of children presenting with micropenis (penis length less than or equal to 2.5 cm) were treated according to 2 different therapeutic schedules. The first consisted of the transcutaneous administration of testosterone propionate (4 mg twice a day) and the second of the intramuscular injection of sustained action testosterone enanthate (25 mg every 2 weeks). Only the intramuscular treatment was able to induce a normal and durable penis growth, owing to the hyperplastic action that the testosterone injection exerted on the level of the cellular tissues of the penis. Using testosterone enanthate dosages varying from 25 to 50 mg, the risks for an abnormal acceleration of growth and bone age seem to be minimized.
两组患有小阴茎（阴茎长度小于或等于2.5厘米）的儿童按照两种不同的治疗方案进行治疗。第一种方案是经皮给予丙酸睾酮（每日两次，每次4毫克），第二种方案是肌肉注射长效庚酸睾酮（每两周25毫克）。只有肌肉注射治疗能够诱导阴茎正常且持久地生长，这是由于睾酮注射对阴茎细胞组织水平产生的增生作用。使用25至50毫克不等的庚酸睾酮剂量，生长和骨龄异常加速的风险似乎降至最低。
