Díaz Gómez L A, Lagarón Comba E, Pérez Escariz P
An Esp Pediatr. 1982 Feb;16(2):145-52.
Hypoplasia of penis which is frequently associated with hipospadias is important when a surgical treatment of this malformation is to undertaken. The decision to increase the dimensions of the penis before surgery by means of hormone treatments is based on good surgical results obtained in very young patients with hypoplasia. The authors have conducted a study involving 76 boys with hipospadias over a period of four years. One group of 37 boys was treated with corionic gonadotrophines by injection during a period of eight weeks. The second group of 39 boys was treated with testosterone cream (2%) topically during one month. Measurements were taken before and after the treatments using four parameters, and the boys were separated according to age. The results showed a more favorable response to testosterone cream in comparison to the injections of corionic gonadotrophines.
阴茎发育不全常与尿道下裂相关，在对这种畸形进行手术治疗时很重要。通过激素治疗在手术前增大阴茎尺寸的决定是基于在非常年幼的阴茎发育不全患者中获得的良好手术效果。作者在四年时间里对76名患有尿道下裂的男孩进行了一项研究。一组37名男孩在八周内通过注射绒毛膜促性腺激素进行治疗。另一组39名男孩在一个月内局部使用2%的睾酮乳膏进行治疗。使用四个参数在治疗前后进行测量，并根据年龄对男孩进行分组。结果表明，与注射绒毛膜促性腺激素相比，睾酮乳膏的反应更有利。
