David T J, Wells F E, Sharpe T C, Gibbs A C
Br J Dermatol. 1984 Nov;111(5):597-601. doi: 10.1111/j.1365-2133.1984.tb06630.x.
Serum zinc was measured by atomic absorption spectrophotometry in sixty-five children with atopic eczema and seventy-nine control children. The mean serum zinc of the patients, (11.4 +/- 2.0 mumol/l) was significantly lower than that of the controls (13.7 +/- 2.3 mumol/l, P less than 0.0001). There was no significant correlation between the patients' serum zinc concentration and either the height/weight centile or a subjective assessment of severity and extent of the eczema. Of eleven patients with serum zinc below 10 mumol/l, six had recurrent infections of the skin, a significantly greater proportion than in patients whose serum zinc was 10 mumol/l or above. It is suspected that the decreased plasma zinc concentration in children with eczema is a non-specific consequence of the dermatological disorder, and therefore there is no indication for zinc supplementation.
采用原子吸收分光光度法对65例特应性皮炎患儿和79例对照儿童进行血清锌检测。患者的平均血清锌水平为（11.4±2.0μmol/L），显著低于对照组（13.7±2.3μmol/L，P<0.0001）。患者的血清锌浓度与身高/体重百分位数或湿疹严重程度及范围的主观评估之间均无显著相关性。在11例血清锌低于10μmol/L的患者中，6例有皮肤反复感染，这一比例显著高于血清锌为10μmol/L或以上的患者。怀疑湿疹患儿血浆锌浓度降低是皮肤病的非特异性后果，因此没有补锌的指征。
