特应性皮炎中的胃肠道症状
Gastrointestinal symptoms in atopic eczema.
作者信息
Caffarelli C, Cavagni G, Deriu F M, Zanotti P, Atherton D J
机构信息
Clinica Pediatrica, Università di Parma, Italy.
出版信息
Arch Dis Child. 1998 Mar;78(3):230-4. doi: 10.1136/adc.78.3.230.
AIMS
To determine the prevalence of gastrointestinal symptoms in children with eczema and the association of such symptoms with the extent of eczema or skin prick test results.
METHODS
Sixty five children with atopic eczema and a control group matched for age and sex were recruited. Their parents completed a questionnaire about the children's gastrointestinal symptoms. The children's skin was examined; their weight, height, and abdominal circumference were measured; and skin prick tests were carried out.
RESULTS
Gastrointestinal symptoms, especially diarrhea, vomiting, and regurgitation, were more common in the children with eczema. Diarrhea appeared to be associated with the ingestion of specific foods. Gastrointestinal symptoms were related to diffuse eczema and positive skin prick tests to foods. There was no anthropometric differences between the patient and control groups.
CONCLUSIONS
A gastrointestinal disorder is common in children with eczema, especially with diffuse distribution. This may be responsible for substantial symptoms and may play a part in the pathogenesis of the disease and in the failure to thrive with which it is sometimes associated.
目的
确定湿疹患儿胃肠道症状的患病率，以及此类症状与湿疹程度或皮肤点刺试验结果之间的关联。
方法
招募了65名患有特应性湿疹的儿童，并设立了一个年龄和性别相匹配的对照组。他们的父母填写了一份关于儿童胃肠道症状的问卷。对儿童的皮肤进行检查；测量他们的体重、身高和腹围；并进行皮肤点刺试验。
结果
胃肠道症状，尤其是腹泻、呕吐和反流，在湿疹患儿中更为常见。腹泻似乎与特定食物的摄入有关。胃肠道症状与弥漫性湿疹和对食物的皮肤点刺试验阳性有关。患者组和对照组之间在人体测量学方面没有差异。
结论
胃肠道疾病在湿疹患儿中很常见，尤其是在皮疹呈弥漫分布的患儿中。这可能是导致明显症状的原因，并且可能在疾病的发病机制以及有时与之相关的生长发育不良中起作用。
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