Abecassis M, Makowka L, Langer B, Taylor B
Can J Surg. 1984 Nov;27(6):561-6.
There has been a resurgence of interest in injection sclerotherapy as a means of controlling and preventing variceal hemorrhage. This report reviews and evaluates the early experience with this procedure at the Toronto General Hospital. From May 1979 to January 1983, 39 patients underwent 73 separate treatment sessions (rigid 23, flexible 50), during active bleeding (3), during hospitalization for variceal hemorrhage but after cessation of bleeding (35) and during elective admission to hospital expressly for sclerotherapy (35). Follow-up was obtained for 38 patients (98%). The overall rate of rebleeding was 27%. Complications occurred in 13 patients (33%). Ten patients died; in 2, death was directly attributable to a complication of sclerotherapy. From this preliminary experience the authors conclude that complications of sclerotherapy are frequent and potentially life-threatening, so more prospective randomized trials are needed before its role in the treatment of bleeding varices is clear.
作为控制和预防静脉曲张出血的一种手段，注射硬化疗法重新引起了人们的关注。本报告回顾并评估了多伦多综合医院开展该手术的早期经验。1979年5月至1983年1月，39例患者接受了73次单独治疗（硬式内镜23次，软式内镜50次），其中3例在活动性出血期间接受治疗，35例在因静脉曲张出血住院但出血停止后接受治疗，35例在专门为硬化疗法而择期入院时接受治疗。对38例患者（98%）进行了随访。再出血的总体发生率为27%。13例患者（33%）出现并发症。10例患者死亡；其中2例死亡直接归因于硬化疗法的并发症。基于这一初步经验，作者得出结论，硬化疗法的并发症很常见且可能危及生命，因此在其在治疗出血性静脉曲张中的作用明确之前，需要进行更多的前瞻性随机试验。
