高、低光化学空气污染地区非吸烟者的慢性阻塞性肺疾病患病率
COPD prevalence in nonsmokers in high and low photochemical air pollution areas.
作者信息
Hodgkin J E, Abbey D E, Euler G L, Magie A R
出版信息
Chest. 1984 Dec;86(6):830-8. doi: 10.1378/chest.86.6.830.
The prevalence of respiratory symptoms, as ascertained by questionnaire, was evaluated in 6,666 nonsmokers who had lived for at least 11 years in either a high photochemical pollution area (4,379 individuals) or a low photochemical pollution area (2,287 individuals). Of these, 5,178 had never smoked, and none was currently smoking. The risk estimate for "definite" COPD, as defined in this study, was 15 percent higher in the high pollution area (p = 0.03), after adjusting for sex, age, race, education, occupational exposure, and past smoking history. Past smokers had a risk estimate 22 percent higher than never smokers (p = 0.01). Multivariate analysis showed a significant effect of air pollution on the prevalence of "definite" COPD which univariate analysis failed to demonstrate.
通过问卷调查确定的呼吸道症状患病率，在6666名非吸烟者中进行了评估，这些人在高光化学污染地区（4379人）或低光化学污染地区（2287人）居住了至少11年。其中，5178人从未吸烟，且目前无人吸烟。在对性别、年龄、种族、教育程度、职业暴露和既往吸烟史进行调整后，本研究定义的“确诊”慢性阻塞性肺疾病（COPD）的风险估计在高污染地区高15%（p = 0.03）。既往吸烟者的风险估计比从不吸烟者高22%（p = 0.01）。多变量分析显示空气污染对“确诊”COPD患病率有显著影响，而单变量分析未能证明这一点。
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