[锫-249对大鼠的致瘤作用]
[The blastomogenic effect of 249Bk in rats].
作者信息
Moskalev Iu I, Zalikin G A, Zhorova E S, Nisimov P G
出版信息
Eksp Onkol. 1984;6(3):36-8.
PMID:6499740
Abstract
It is shown that 249Bk nitrate injected intraperitoneally in a wide range of doses to albino mongrel female rats is preferentially accumulated in the bony tissue (39.8%) and liver (18.4%). Incorporation of 249Bk to rats results in development of osteosarcomas, neoplasms of hemopoietic and lymphoid tissues, mammary tumours, thyroid and pituitary glands.
摘要
结果表明，向杂种雌性白化大鼠腹腔内注射各种剂量的硝酸锫-249后，其在骨组织（39.8%）和肝脏（18.4%）中优先蓄积。大鼠摄入锫-249会导致骨肉瘤、造血和淋巴组织肿瘤、乳腺肿瘤、甲状腺和垂体肿瘤的发生。
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