Oksman A Ia, Lisochkin B G, Marikhina B L, Eremeeva A A
Eksp Onkol. 1984;6(1):57-61.
The fractional composition of chromatin proteins and an electron-microscopic pattern of cell ultrastructure of the Ehrlich ascite tumours and ascite lymphoma NK/Ly were studied when suppressing their growth by a combined action of cyclophosphane and polyene antibiotic. Changes in the fractional composition of chromatin proteins were found under the effect of levorin. A sharp increase in this effect and summation of heterogeneous morphological changes provoked by each of the preparation occur under a combined application of the preparations.
研究了环磷酰胺和多烯抗生素联合作用抑制艾氏腹水瘤和腹水淋巴瘤NK/Ly生长时，染色质蛋白的组分构成及细胞超微结构的电子显微镜图像。发现左霉素作用下染色质蛋白的组分构成发生了变化。联合应用这两种制剂时，该作用急剧增强，且每种制剂引发的不同形态学变化会叠加。
