Gus'kova T A, Liberman S S, Romanova L K, Chicherina L A
Farmakol Toksikol. 1984 Sep-Oct;47(5):90-3.
It has been shown in experiments on rats that phenobarbital, hexamidine and benzonal administered in doses producing the induction of liver microsomal enzymes reduce the total toxic action of dioxydin and pathological alterations in the adrenals induced by dioxydin. A possible mechanism of the effect under consideration is discussed.
在对大鼠的实验中已表明,给予能诱导肝微粒体酶的剂量的苯巴比妥、己脒定和苯佐那尔,可降低二氧嘧啶的总毒性作用以及由二氧嘧啶引起的肾上腺病理改变。文中讨论了所考虑的这种效应的可能机制。