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低温状态下中性粒细胞在体外和体内的迁移

Neutrophil migration in vitro and in vivo during hypothermia.

作者信息

Biggar W D, Bohn D J, Kent G, Barker C, Hamilton G

出版信息

Infect Immun. 1984 Dec;46(3):857-9. doi: 10.1128/iai.46.3.857-859.1984.

DOI:10.1128/iai.46.3.857-859.1984
PMID:6500715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC261627/
Abstract

The effect of hypothermia on pig leukocyte migration in vitro and in vivo was studied. Neutrophil chemotaxis in vitro under agarose was significantly impaired at 29 degrees C (2.7 +/- 0.6 [mean +/- standard error]; 37 degrees C, 7.1 +/- 1.1). Leukocytes isolated from hypothermic pigs and tested at 37 degrees C migrated normally (7.8 +/- 0.6). Neutrophil and monocyte migration in vivo was markedly reduced at 29 degrees C. Reduced inflammatory responses may contribute to increased infections during hypothermia.

摘要

研究了低温对猪体外和体内白细胞迁移的影响。在29摄氏度时，琼脂糖下的体外中性粒细胞趋化性显著受损（2.7±0.6[平均值±标准误差]；37摄氏度时为7.1±1.1）。从低温猪分离出的白细胞在37摄氏度下测试时迁移正常（7.8±0.6）。在29摄氏度时，体内中性粒细胞和单核细胞的迁移明显减少。炎症反应减弱可能导致低温期间感染增加。

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1
Neutrophil migration in vitro and in vivo during hypothermia.低温状态下中性粒细胞在体外和体内的迁移
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2
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Chemotaxis of porcine neutrophils under agarose.琼脂糖下猪中性粒细胞的趋化作用。
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