恩肽霉素（BMY - 28117），一种新型缩酚酸肽类抗生素。II. 结构测定。
Empedopeptin (BMY-28117), a new depsipeptide antibiotic. II. Structure determination.
作者信息
Sugawara K, Numata K, Konishi M, Kawaguchi H
出版信息
J Antibiot (Tokyo). 1984 Sep;37(9):958-64. doi: 10.7164/antibiotics.37.958.
PMID:6501109
Abstract
Structure of a new antibiotic, empedopeptin, has been determined. It is a cyclic depsipeptide composed of two mol of D-serine and one mol each of beta-hydroxytetradecanoic acid, L-arginine, D- and L-proline, L-3-hydroxyproline and D- and L-beta-hydroxyaspartic acid. The sequence of these moieties was established by partial hydrolysis and mass spectral analysis of the antibiotic.
摘要
一种新型抗生素恩培多普汀的结构已被确定。它是一种环缩肽，由两摩尔的D-丝氨酸和一摩尔的β-羟基十四烷酸、L-精氨酸、D-和L-脯氨酸、L-3-羟基脯氨酸以及D-和L-β-羟基天冬氨酸组成。通过对抗生素进行部分水解和质谱分析确定了这些部分的序列。
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