通过克罗恩病患者和健康受试者的粪便菌群诱导大鼠产生针对真杆菌属、消化链球菌属和粪球菌属菌种的血清凝集素。
Induction in rats of serum agglutinins to Eubacterium, Peptostreptococcus and Coprococcus species by the faecal flora from patients with Crohn's disease and healthy subjects.
作者信息
Hazenberg M P, Van de Merwe J P, Custers-Van Lieshout L M, Pennock-Schröder A M
出版信息
J Hyg (Lond). 1984 Oct;93(2):345-8. doi: 10.1017/s0022172400064895.
Sera from patients with Crohn's disease more often than those from other subjects contain agglutinins against anaerobic coccoid rods, identified as Peptostreptococcus productus, Eubacterium contortum (two strains) and Coprococcus comes. The presence of antigens of the four coccoid rods in faeces of patients with Crohn's disease and healthy subjects was investigated by inoculation of rats with faecal suspensions. Antigens of the coccoid rods were detected in faeces from both patients with Crohn's disease and healthy subjects.
与其他受试者相比，克罗恩病患者的血清中更常含有针对厌氧类球菌杆的凝集素，这些菌被鉴定为产物消化链球菌、扭曲真杆菌（两株）和黏性粪球菌。通过给大鼠接种粪便悬液，研究了克罗恩病患者和健康受试者粪便中这四种类球菌杆抗原的存在情况。在克罗恩病患者和健康受试者的粪便中均检测到了类球菌杆的抗原。
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