Joint report of the B lymphocyte specificities workshop of the France-one region.

The analysis of 182 selected anti-B cell sera on 102 cells allowed us to identifysseveral clusters of sera. They showed no correlation with HLA-A, B or C specificities but many associations with the HLA-D determinants. In 10 families, most of these sera segregated with HLA, and five recombinants showed a linkage with the BD or D end part of the MHC. The panel distribution and the family analysis indicated that at least one (the Ly-Li system) and probably two segregant series could exist close to the HLA-D locus.