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职业性癌症监测方法。

Approaches to surveillance of occupational cancer.

作者信息

Wegman D H

出版信息

J Toxicol Clin Toxicol. 1984;22(3):239-59. doi: 10.3109/15563658408992558.

Abstract

The overall number of deaths from cancer is increasing. The absolute magnitude of this increase is in debate. Unfortunately, we are unable to estimate the interactions between two or more agents such as cigarettes and asbestos. None of the appropriate studies is precisely able to know the exact exposure to carcinogens. Regardless of the percentage of cancers related to the workplace, the numbers are clearly clinically significant. It is important to present to physicians medical conditions which have an increased probability of resulting from occupational exposure. This will allow clinics, hospitals and health departments to seek evidence of changing patterns or clusters of listed diseases. Individual physicians with a high index of suspicion play an important role in detecting occupational cancers. The current state of the art is, that with rare exceptions, a good occupational history which contributes to a reasonable diagnosis with appropriate background information is the best way for the practicing doctor to detect occupational cancers. All health care providers should look beyond cigarettes as the only cause of cancer worth noting in order to implement primary preventive medicine strategies.

摘要

癌症死亡的总体数量正在增加。这种增长的绝对幅度仍存在争议。不幸的是,我们无法估计香烟和石棉等两种或更多因素之间的相互作用。没有任何一项合适的研究能够确切了解致癌物的具体暴露情况。无论与工作场所相关的癌症比例如何,其数量在临床上显然具有重要意义。向医生介绍因职业暴露而导致患病概率增加的医疗状况非常重要。这将使诊所、医院和卫生部门能够寻找所列疾病模式变化或聚集的证据。高度怀疑的个体医生在发现职业性癌症方面发挥着重要作用。目前的技术水平是,除了极少数例外情况,一份有助于在适当背景信息下做出合理诊断的良好职业史是执业医生发现职业性癌症的最佳方法。所有医疗保健提供者都不应仅将香烟视为值得关注的唯一致癌原因,以便实施初级预防医学策略。

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