Mitchison T, Kirschner M
Nature. 1984;312(5991):237-42. doi: 10.1038/312237a0.
We report here that microtubules in vitro coexist in growing and shrinking populations which interconvert rather infrequently. This dynamic instability is a general property of microtubules and may be fundamental in explaining cellular microtubule organization.
我们在此报告,体外微管共存于生长和收缩群体中,它们之间的相互转换相当罕见。这种动态不稳定性是微管的普遍特性,可能是解释细胞微管组织的基础。