Wagner V, Wagnerová M, Mádlo Z, Zavázal V
Physiol Bohemoslov. 1984;33(5):437-46.
Blood and saliva were collected in the autumn and spring from a group of schoolchildren (39 girls, 35 boys) with a mean age of 11.4 years. Serum immunoglobulin IgG, IgA, IgM and IgE, alpha 1-antitrypsin (A 1-AT), alpha 2 macroglobulin (A 2M), transferrin (TRF), ceruloplasmin (CPL), lysozyme (LYS) and pertussis (PE) antibody levels were determined. Calcium (Ca2+) and total serum protein levels were also determined. Secretory IgA (sIgA) and secretory lysozyme (sLYS) levels were assessed in the saliva. A highly significant drop in Ca2+ levels was found in the spring in boys, while in girls there was only a greater scatter of the values. Mean IgG, IgA and IgM values fell significantly in the spring in both sexes, but IgE levels fell significantly only in boys. PE levels rose significantly in the spring in girls. Among the other proteins, all the values rose in boys, except for TRF, whose levels fell. In girls, LYS and TRF levels rose, but all the other values fell. The coefficients of correlation between Ca2+ and the tested proteins showed a significant relationship only for A 2M and PE in girls and only for the total protein level in boys; in boys, the determination coefficient for sIgA and IgM was over 10%. The results do not testify to the existence of a close relationship between blood Ca2+ levels and Ig and other blood protein levels.
在秋季和春季从一组平均年龄为11.4岁的学童（39名女孩，35名男孩）中采集血液和唾液。测定血清免疫球蛋白IgG、IgA、IgM和IgE、α1 -抗胰蛋白酶（A1 - AT）、α2巨球蛋白（A2M）、转铁蛋白（TRF）、铜蓝蛋白（CPL）、溶菌酶（LYS）和百日咳（PE）抗体水平。还测定了钙（Ca2 +）和总血清蛋白水平。评估唾液中的分泌型IgA（sIgA）和分泌型溶菌酶（sLYS）水平。发现春季男孩的Ca2 +水平显著下降，而女孩的数值仅更分散。春季两性的平均IgG、IgA和IgM值均显著下降，但IgE水平仅在男孩中显著下降。春季女孩的PE水平显著升高。在其他蛋白质中，男孩的所有数值均升高，但TRF水平下降。在女孩中，LYS和TRF水平升高，但其他所有数值均下降。Ca2 +与所检测蛋白质之间的相关系数仅在女孩中显示A2M和PE有显著关系，在男孩中仅与总蛋白水平有显著关系；在男孩中，sIgA和IgM的决定系数超过10%。结果并未证明血钙水平与Ig及其他血液蛋白水平之间存在密切关系。
