Wagner V, Munzarová J, Wagnerová M, Zavázal V, Wokounová D, Kríź J
Czech Med. 1981;4(4):197-202.
In a previous study the levels of nine serum and two salivary proteins were measured in a group of 80 children. Some significant differences of mean levels were found between the group of children, who remained well and who fell ill in the school year following the examination. In the present study the discrimination analysis was performed between both mentioned ill and healthy subgroups of children, referring to possible interaction of two protein tested. The comparison showed significant difference between double-protein combinations in 17 from 36 possibilities in girls subgroup. Relevant double combinations were assessed only in five of nine tested proteins: IgE, IgA, CPL, TRF and A 1-AT. Two combinations revealed the greatest significance: IgE with IgA, and IgE with CPL. No such significance was found in boys subgroup. The results suggest that prevalence of respiratory disease in influenced not only by previous levels of some single proteins, how it was found in the first paper, but also by the interactions of certain proteins.
在之前的一项研究中，对一组80名儿童的9种血清蛋白和2种唾液蛋白水平进行了测量。在检查后的学年里，在保持健康的儿童组和生病的儿童组之间发现了一些平均水平的显著差异。在本研究中，针对上述生病和健康的儿童亚组进行了判别分析，涉及两种检测蛋白的可能相互作用。比较显示，在女孩亚组的36种可能性中，有17种双蛋白组合存在显著差异。仅在9种检测蛋白中的5种（IgE、IgA、CPL、TRF和A 1-AT）中评估了相关的双组合。两种组合显示出最大的显著性：IgE与IgA，以及IgE与CPL。在男孩亚组中未发现此类显著性。结果表明，呼吸系统疾病的患病率不仅受如第一篇论文中所发现的某些单一蛋白的先前水平影响，还受某些蛋白之间相互作用的影响。
