Raju S, Didlake R H, Cayirli M, Turner M D, Grogan J B, Achord J
Transplantation. 1984 Dec;38(6):561-6. doi: 10.1097/00007890-198412000-00001.
Cyclosporine prolonged the survival of ectopic small bowel allografts in a canine model. A 9-fold increase in mean survival as compared with controls was obtained. Addition of prednisone to cyclosporine did not result in further graft prolongation, but improved the gross and histological appearance of the allograft. Monitoring the motility and histology of the allograft appears to be useful in predicting approaching rejection. Xylose absorption was not helpful in this regard. A new technique for measuring fat absorption in the transplant is described. Following allografting, fat absorption is resumed by 14 days posttransplantation.
环孢素可延长犬异位小肠同种异体移植的存活时间。与对照组相比，平均存活时间延长了9倍。在环孢素基础上加用泼尼松并不能进一步延长移植物存活时间，但改善了同种异体移植的大体和组织学表现。监测同种异体移植的运动功能和组织学变化似乎有助于预测即将发生的排斥反应。木糖吸收在这方面并无帮助。本文描述了一种测量移植肠脂肪吸收的新技术。同种异体移植后，移植后14天脂肪吸收恢复。
