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环孢素和泼尼松用于犬的成功小肠同种异体移植。

Successful small bowel allotransplantation in dogs with cyclosporine and prednisone.

作者信息

Diliz-Perez H S, McClure J, Bedetti C, Hong H Q, de Santibanes E, Shaw B W, van Thiel D, Iwatsuki S, Starzl T E

出版信息

Transplantation. 1984 Feb;37(2):126-9. doi: 10.1097/00007890-198402000-00002.

Abstract

Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

摘要

12只狗接受了几乎整个小肠的原位移植;免疫抑制采用环孢素和泼尼松。一半的狗存活至少1个月,三分之一存活至少4个月。其中两只动物分别在550天和555天后仍存活。营养维持以及D-木糖和脂肪的吸收情况优于患有医源性短肠综合征的对照动物,但明显差于正常狗。

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引用本文的文献

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Small bowel transplantation.小肠移植
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本文引用的文献

1
Homografts of the small bowel.
Surg Forum. 1960;10:197-201.
2
Homotransplantation of multiple visceral organs.多个内脏器官的同种移植
Am J Surg. 1962 Feb;103:219-29. doi: 10.1016/0002-9610(62)90491-9.
8
Absorption studies in canine jejunal allografts.犬空肠同种异体移植的吸收研究。
Ann Surg. 1971 Jul;174(1):101-8. doi: 10.1097/00000658-197107010-00016.

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