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环孢素和泼尼松用于犬的成功小肠同种异体移植。

Successful small bowel allotransplantation in dogs with cyclosporine and prednisone.

作者信息

Diliz-Perez H S, McClure J, Bedetti C, Hong H Q, de Santibanes E, Shaw B W, van Thiel D, Iwatsuki S, Starzl T E

出版信息

Transplantation. 1984 Feb;37(2):126-9. doi: 10.1097/00007890-198402000-00002.

DOI:10.1097/00007890-198402000-00002
PMID:6695451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2976623/
Abstract

Twelve dogs had transplantation of almost the entire small intestine in the orthotopic location; immunosuppression was with cyclosporine and prednisone. Half the dogs had survival of at least one month, and a third lived for at least four months. Two of the animals are still living after 550 and 555 days. Maintenance of nutrition, and absorption of D-xylose and fat were better than in control animals with an iatrogenic short gut syndrome, but distinctly worse than that of normal dogs.

摘要

12只狗接受了几乎整个小肠的原位移植;免疫抑制采用环孢素和泼尼松。一半的狗存活至少1个月,三分之一存活至少4个月。其中两只动物分别在550天和555天后仍存活。营养维持以及D-木糖和脂肪的吸收情况优于患有医源性短肠综合征的对照动物,但明显差于正常狗。

相似文献

1
Successful small bowel allotransplantation in dogs with cyclosporine and prednisone.环孢素和泼尼松用于犬的成功小肠同种异体移植。
Transplantation. 1984 Feb;37(2):126-9. doi: 10.1097/00007890-198402000-00002.
2
Morphologic studies of intestinal allograft rejection. Immunosuppression with cyclosporine.肠道同种异体移植排斥反应的形态学研究。环孢素免疫抑制。
Dis Colon Rectum. 1984 Apr;27(4):228-34. doi: 10.1007/BF02553789.
3
Problems in absorption and immunosuppression after entire intestinal allotransplantation.全小肠同种异体移植后的吸收及免疫抑制问题。
Am J Surg. 1972 Mar;123(3):297-303. doi: 10.1016/0002-9610(72)90289-9.
4
Experimental small bowel transplantation utilizing cyclosporine.使用环孢素的实验性小肠移植
Transplantation. 1984 Dec;38(6):561-6. doi: 10.1097/00007890-198412000-00001.
5
Small intestinal transplantation. A closer reality.小肠移植。更近的现实。
Dis Colon Rectum. 1985 Dec;28(12):908-11. doi: 10.1007/BF02554303.
6
Total orthotopic small bowel transplantation with cyclosporine.环孢素辅助下的全原位小肠移植
Transplantation. 1987 Oct;44(4):469-74. doi: 10.1097/00007890-198710000-00002.
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Functional monitors of rejection in small intestinal transplants.小肠移植排斥反应的功能监测器
Am J Surg. 1984 Jan;147(1):152-8. doi: 10.1016/0002-9610(84)90050-3.
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Cyclosporine absorption in intestinal transplantation.肠道移植中环孢素的吸收
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Experimental small-bowel transplantation: alternative strategies for graft prolongation.实验性小肠移植:延长移植物存活时间的替代策略。
J Pediatr Surg. 1989 Dec;24(12):1253-7. doi: 10.1016/s0022-3468(89)80562-7.

引用本文的文献

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Immunomodulation for intestinal transplantation by allograft irradiation, adjunct donor bone marrow infusion, or both.通过对移植物进行照射、辅助输注供体骨髓或两者结合来实现肠道移植的免疫调节。
Transplantation. 2000 Dec 15;70(11):1632-41. doi: 10.1097/00007890-200012150-00016.
2
Absorptive function following small intestinal transplantation.
Dig Dis Sci. 1998 Sep;43(9):1925-30. doi: 10.1023/a:1018816622510.
3
Functional aspects of small bowel transplantation: past, present, and future.小肠移植的功能方面:过去、现在与未来。
Gut. 1994 Oct;35(10):1338-42. doi: 10.1136/gut.35.10.1338.
4
Gastrointestinal motility in the immediate postoperative period after intestinal transplantation, with special reference to acute rejection.肠道移植术后即刻的胃肠动力,特别涉及急性排斥反应。
Transplant Proc. 1994 Jun;26(3):1657-8.
5
Pancreaticoduodenal transplantation in humans.人类胰十二指肠移植
Surg Gynecol Obstet. 1984 Sep;159(3):265-72.
6
Small bowel transplantation.小肠移植
World J Surg. 1985 Dec;9(6):860-7. doi: 10.1007/BF01655390.
7
Transplantation of multiple abdominal viscera.多个腹部脏器移植
JAMA. 1989 Mar 10;261(10):1449-57.
8
Current status of intestinal transplantation.肠道移植的现状
Gut. 1989 Dec;30(12):1771-82. doi: 10.1136/gut.30.12.1771.
9
Successful segmental intestinal transplantation in enterectomized pigs.在小肠切除的猪身上成功进行节段性小肠移植。
Ann Surg. 1990 Feb;211(2):158-64. doi: 10.1097/00000658-199002000-00007.
10
Canine total orthotopic small bowel transplantation under FK 506.在使用FK 506的情况下进行犬全原位小肠移植。
Transplant Proc. 1991 Dec;23(6):3240-2.

本文引用的文献

1
Homografts of the small bowel.
Surg Forum. 1960;10:197-201.
2
Homotransplantation of multiple visceral organs.多个内脏器官的同种移植
Am J Surg. 1962 Feb;103:219-29. doi: 10.1016/0002-9610(62)90491-9.
3
Structure and function of small bowel allografts in the dog: immunosuppression with cyclosporin A.犬小肠同种异体移植的结构与功能:环孢素A免疫抑制作用
Can J Surg. 1982 Jan;25(1):51-5.
4
Survival of homografts of the intestine with and without immunosuppression.肠道同种移植在免疫抑制和未免疫抑制情况下的存活情况。
Surgery. 1966 Dec;60(6):1203-10.
5
Intestinal transplantation: laboratory experience and report of a clinical case.肠道移植:实验室经验及一例临床病例报告
Am J Surg. 1971 Feb;121(2):150-9. doi: 10.1016/0002-9610(71)90092-4.
6
Effect of antilymphocyte serum and other immunosuppressive agents on canine jejunal allografts.抗淋巴细胞血清及其他免疫抑制剂对犬空肠同种异体移植的影响。
Ann Surg. 1970 Jan;171(1):51-60. doi: 10.1097/00000658-197001000-00008.
7
Prolongation of survival of jejunal homografts in dogs treated with azathioprine (imuran).用硫唑嘌呤(依木兰)治疗的犬空肠同种移植存活期的延长。
Br J Surg. 1966 Feb;53(2):134-8. doi: 10.1002/bjs.1800530212.
8
Absorption studies in canine jejunal allografts.犬空肠同种异体移植的吸收研究。
Ann Surg. 1971 Jul;174(1):101-8. doi: 10.1097/00000658-197107010-00016.
9
Transplantation of stomach, intestine, and pancreas: experimental and clinical observations.胃、肠及胰腺移植:实验与临床观察
Surgery. 1967 Oct;62(4):721-41.