Lauer K, Firnhaber W, Reining R, Leuchtweis B
Acta Neurol Scand. 1984 Oct;70(4):257-65. doi: 10.1111/j.1600-0404.1984.tb00823.x.
An epidemiological field-survey on multiple sclerosis (MS) was carried out in the southern part of the state of Hesse (West Germany). Out of 472 patients primarily ascertained, 75% could finally be accepted as definite or probable MS cases. Cross-checking of the 3 sources for case-finding (practitioners and specialists, neurological hospital, MS society) revealed that case-finding in all and especially that of definite and probable MS cases was rather complete. The overall prevalence rate was 58.3, the annual incidence 2.15 and the mortality rate 2.0 per 100,000. Male patients showed a faster course than females. The prevalence in immigrants who mostly originated from Mediterranean countries, was significantly lower (14.3 per 100,000) than the prevalence in the German population (63.1 per 100,000).
在黑森州（西德）南部开展了一项关于多发性硬化症（MS）的流行病学实地调查。在最初确定的472名患者中，最终75%可被认定为确诊或疑似MS病例。对三种病例发现来源（从业者和专家、神经科医院、MS协会）进行交叉核对后发现，所有病例尤其是确诊和疑似MS病例的发现工作相当完整。总体患病率为每10万人58.3例，年发病率为每10万人2.15例，死亡率为每10万人2.0例。男性患者的病程比女性更快。大多来自地中海国家的移民患病率（每10万人14.3例）显著低于德国人口的患病率（每10万人63.1例）。
