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The effect of a single dose of metrifonate on Schistosoma haematobium infection in Egyptian school children.

作者信息

el Kholy A, Boutros S, Tamara F, Warren K S, Mahmoud A A

出版信息

Am J Trop Med Hyg. 1984 Nov;33(6):1170-2. doi: 10.4269/ajtmh.1984.33.1170.

DOI:10.4269/ajtmh.1984.33.1170
PMID:6507729
Abstract

Egyptian school children infected with Schistosoma haematobium and treated with a single dose of metrifonate, 10 mg/kg body weight, had a marked reduction in urine egg counts reaching 90% during a 30-week follow-up. While cure rate was higher among lightly infected persons, percentage reduction in egg counts was greater among the heavily infected. After a summer period of probable high risk exposure reinfection rate in those children who were treated and cured was 4.7% as compared to 6% in previously uninfected children.

摘要

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Metrifonate in the control of urinary schistosomiasis in Zanzibar.敌百虫在桑给巴尔控制尿路血吸虫病中的应用
Bull World Health Organ. 1990;68(6):721-30.
2
Effect of a single oral dose of metrifonate on human plasma cholinesterase levels.
Bull Environ Contam Toxicol. 1991 Nov;47(5):641-5. doi: 10.1007/BF01701128.