Mohan Kumar V, Datta S, Chhina G S, Gandhi N, Singh B
Brain Res. 1984 Nov 26;322(2):322-5. doi: 10.1016/0006-8993(84)90125-2.
The study makes an attempt to find out the action of norepinephrine (NE) and phenoxybenzamine (PB), applied at medial preoptic area (mPOA), in altering the sleep-awake responses, in free moving rats, which has not yet been reported. Effects of application of NE during day and PB during night, at mPOA, on sleep-awake responses, were compared with application of saline during identical periods. Application of NE produced arousal, whereas, PB produced the opposite effect. The findings are suggestive of the involvement of NE terminals at mPOA in normal arousal.
本研究试图探究在内侧视前区（mPOA）应用去甲肾上腺素（NE）和酚苄明（PB）对自由活动大鼠睡眠-觉醒反应的影响，这方面尚未见报道。将白天在mPOA应用NE、夜间应用PB对睡眠-觉醒反应的影响，与相同时间段应用生理盐水的情况进行比较。应用NE产生觉醒，而PB产生相反的效果。这些发现提示mPOA处的NE终末参与正常觉醒过程。
