Trobaugh G B, Hallstrom A P, Kennedy J W
Cathet Cardiovasc Diagn. 1984;10(6):561-72. doi: 10.1002/ccd.1810100606.
Interobserver reproducibility of single plane contrast angiographic measurements of end-diastolic volume (EDV/m2), end-systolic volume (ESV/m2), stroke volume (SV/m2), and ejection fraction (EF) was studied in two groups of patients. The first group (n = 42) was an unselected, consecutive series of patients in which the calculations of volume were performed manually, representing day-to-day results from a clinical quantitative angiographic laboratory. The second group (n = 31) was selected on the basis of optimal filming technique and volume calculations were performed digitally with the aid of a computer. This group characterizes the reproducibility that could be attained for investigational purposes. In the selected group, interobserver reproducibility of four regional ejection fractions was determined. The correlation coefficient (r), standard error of the estimate (Sy.x), average difference, and 95% confidence limits are given. Measurement variation accounted for 9-15% of the variance in this study for EDV/m2 (consecutive series), indicating that caution is needed when relating contrast angiographic measurements to other (e.g., noninvasive) measures of volume by simple linear regression.
在两组患者中研究了舒张末期容积（EDV/m²）、收缩末期容积（ESV/m²）、每搏输出量（SV/m²）和射血分数（EF）的单平面对比血管造影测量的观察者间再现性。第一组（n = 42）是一组未经选择的连续患者，容积计算采用手工方式，代表临床定量血管造影实验室的日常结果。第二组（n = 31）是根据最佳拍摄技术选择的，容积计算借助计算机进行数字化处理。该组代表了为研究目的所能达到的再现性。在选定的组中，测定了四个区域射血分数的观察者间再现性。给出了相关系数（r）、估计标准误差（Sy.x）、平均差异和95%置信限。在本研究中，对于EDV/m²（连续系列），测量变异占方差的9 - 15%，这表明在通过简单线性回归将对比血管造影测量结果与其他（如非侵入性）容积测量结果相关联时需要谨慎。
