Bentivoglio L G, Cuesta A J, Griffith L D, Geczy M
Cardiovasc Res. 1976 May;10(3):283-94. doi: 10.1093/cvr/10.3.283.
Technique and errors of quantitative single plane ventriculography (SPV), and the methods of Dodge and Sandler (Dodge et al, 1962; Sandler and Dodge, 1968) and Greene et al (1967) for determining left ventricular (LV) volume by SPV were evaluated in the intact dog. Stroke volume (SV) and cardiac output (Q) by ventriculography were compared with those obtained by the Fick and dye dilution methods, and their combination. The end-diastolic (EDV) and end-systolic volume (ESV) corrected by appropriate regression equations, the SV (SV=EDV - ESV), and the ejection fraction (EF) were: Dodge and Sandler, 2.26 1.35, 0.91 ml/kg, and 0.42; Greene et al, 2.41, 1.50, 0.91 ml/kg, and 0.39. Using adequate methods, accurate correction for x-ray image magnification, and the appropriate regression equations the standard error of LV volume calculation by single plane radiography, due to unavoidable technical inaccuracies, should not exceed 10% for a single measurement and 5% for the average of two or more successive cardiac cycles. The systematic overestimation of LV volume inherent in ventriculography, and caused by the addition of contrast medium, should not exceed 5% of the true value.
在完整的犬身上评估了定量单平面心室造影术（SPV）的技术和误差，以及Dodge和Sandler（Dodge等人，1962年；Sandler和Dodge，1968年）和Greene等人（1967年）通过SPV测定左心室（LV）容积的方法。将心室造影术测得的每搏量（SV）和心输出量（Q）与通过Fick法、染料稀释法及其联合方法测得的结果进行比较。经适当回归方程校正后的舒张末期容积（EDV）和收缩末期容积（ESV）、SV（SV = EDV - ESV）以及射血分数（EF）分别为：Dodge和Sandler法，2.26、1.35、0.91 ml/kg和0.42；Greene等人法，2.41、1.50、0.91 ml/kg和0.39。采用适当的方法、对X射线图像放大进行准确校正以及使用适当的回归方程，由于不可避免的技术误差，单平面X线摄影计算左心室容积的标准误差，单次测量不应超过10%，两个或更多连续心动周期的平均值不应超过5%。心室造影术中由于注入造影剂而固有的左心室容积系统性高估不应超过真实值的5%。
