Duffy T J, Ray R
Contraception. 1984 Sep;30(3):197-208. doi: 10.1016/0010-7824(84)90083-0.
593 women from a cohort of 8,652 healthy women failed a 1-hr glucose screening test. These 593 women with suspected glucose intolerance were classified as normal or as having impaired glucose tolerance (IGT) or diabetes mellitus (DM) after an oral standard glucose tolerance test (SGTT) and were followed over a mean 8.55 years. No permanent change in glucose status as a result of oral contraceptive use was found in an analysis for impaired glucose tolerance, diabetes mellitus, diabetic symptoms, or use of oral agents and/or insulin. Increased glucose intolerance was observed for women who were older, had a positive family history of diabetes, or were of greater relative weight. Diabetic symptoms correlated most closely with the onset of persistent fasting hyperglycemia.
在8652名健康女性队列中，593名女性1小时葡萄糖筛查试验未通过。这593名疑似糖耐量异常的女性在口服标准葡萄糖耐量试验（SGTT）后被分类为正常、糖耐量受损（IGT）或糖尿病（DM），并随访了平均8.55年。在对糖耐量受损、糖尿病、糖尿病症状或口服药物和/或胰岛素使用情况的分析中，未发现口服避孕药导致葡萄糖状态发生永久性变化。年龄较大、有糖尿病家族史阳性或相对体重较大的女性糖耐量异常增加。糖尿病症状与持续性空腹血糖升高的发生最密切相关。
