维拉帕米对自发性高血压大鼠和正常血压大鼠心肌中Ca2+正性肌力作用抑制作用的差异。
Difference of the inhibitory action of verapamil on the positive inotropic effect of Ca2+ between spontaneously hypertensive and normotensive rat myocardium.
作者信息
Kondo N, Shibata S
出版信息
Experientia. 1984 Dec 15;40(12):1392-3. doi: 10.1007/BF01951906.
PMID:6510495
Abstract
Verapamil, a calcium entry blocker, had a greater inhibitory effect on the positive inotropic effect of excess Ca2+ in SHR than in NWR, suggesting that the cardiac responsiveness to verapamil was enhanced in SHR.
摘要
维拉帕米，一种钙通道阻滞剂，对自发性高血压大鼠（SHR）中过量Ca2+的正性肌力作用的抑制作用比对正常血压大鼠（NWR）更强，这表明自发性高血压大鼠对维拉帕米的心脏反应性增强。
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