Starink T M, Hausman R
J Cutan Pathol. 1984 Oct;11(5):338-44. doi: 10.1111/j.1600-0560.1984.tb00389.x.
Twenty extrafacial lesions from 6 patients with Cowden's disease were studied. Most were hyperkeratotic papillomas that resembled verruca vulgaris, acrokeratosis verruciformis, or hyperkeratotic acanthomas. Small hyperkeratotic papillomas frequently showed abnormalities of the follicular infundibulum. Occasionally, follicular abnormalities were seen without concomitant epidermal hyperplasia. It is concluded that some of the extrafacial lesions may originate from the follicular infundibulum. No evidence of a virus infection was found using an antiserum to papilloma virus.
对6例考登病患者的20处面部以外病变进行了研究。多数为角化过度性乳头状瘤，类似寻常疣、疣状肢端角化症或角化过度性棘皮瘤。小的角化过度性乳头状瘤常显示毛囊漏斗部异常。偶尔可见毛囊异常而无表皮增生。结论是，一些面部以外病变可能起源于毛囊漏斗部。使用乳头瘤病毒抗血清未发现病毒感染证据。
