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川崎病中的循环免疫复合物与粒细胞趋化性

Circulating immune complexes and granulocytes chemotaxis in Kawasaki disease.

作者信息

Miyata K, Kawakami K, Onimaru T, Baba Y, Ono S, Hokonohara M, Yoshinaga M, Terawaki T

出版信息

Jpn Circ J. 1984 Dec;48(12):1350-3. doi: 10.1253/jcj.48.1350.

DOI:10.1253/jcj.48.1350
PMID:6512943
Abstract

Serum immunoglobulin levels, complement titers, circulating immune complex levels, and chemotaxis of granulocytes were evaluated in 32 patients with Kawasaki disease with or without coronary aneurysm. The group of patients with coronary aneurysm showed relatively higher levels of IgG. Regardless of the presence of coronary aneurysm, the level of IgE in the acute phase was higher than that in the convalescent phase. The level of immune complexes was higher in the group of patients with coronary aneurysm (p less than 0.05). There was a low negative correlation between immune complexes and CH50. The chemotaxis of the patients with coronary aneurysm was significantly impaired (p less than 0.01).

摘要

对32例患有或未患有冠状动脉瘤的川崎病患者的血清免疫球蛋白水平、补体滴度、循环免疫复合物水平及粒细胞趋化性进行了评估。患有冠状动脉瘤的患者组显示IgG水平相对较高。无论是否存在冠状动脉瘤,急性期的IgE水平均高于恢复期。冠状动脉瘤患者组的免疫复合物水平较高(p<0.05)。免疫复合物与CH50之间存在低度负相关。冠状动脉瘤患者的趋化性明显受损(p<0.01)。

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Circulating immune complexes and granulocytes chemotaxis in Kawasaki disease.川崎病中的循环免疫复合物与粒细胞趋化性
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