Cantrell R W, Bell R A, Morioka W T
Laryngoscope. 1978 Jun;88(6):994-1005. doi: 10.1288/00005537-197806000-00011.
Acute epiglottitis is a disease with significant mortality. The patient, usually an otherwise healthy pre-school child, develops a sore throat and muffled voice from swollen supraglottic structures, and may progress rapidly to respiratory arrest. Early diagnosis and airway maintenance can prevent these fatalities. Whether to secure an airway by tracheostomy or endotracheal intubation is the subject of much discussion. Nineteen series totalling 738 cases of epiglottitis plus 11 new cases are reviewed. These patients were treated as follows: Tracheostomy = 348 (3 deaths - 0.86%); Endotracheal intubation = 216 (2 deaths - 0.92%); medical management with no artificial airway = 214 (13 deaths - 6.1%). The difference in morbidity and mortality between tracheostomy or nasotracheal intubation is so slight that the choice should be determined by local factors. Medical management with no artificial airway should not be used in children.
急性会厌炎是一种死亡率较高的疾病。患者通常是原本健康的学龄前儿童,因声门上结构肿胀而出现咽痛和声音嘶哑,且可能迅速发展为呼吸骤停。早期诊断和气道维持可预防这些死亡。通过气管切开术还是气管插管来确保气道安全是一个备受讨论的话题。本文回顾了19个系列,共计738例会厌炎病例以及11例新病例。这些患者的治疗情况如下:气管切开术 = 348例(3例死亡 - 0.86%);气管插管 = 216例(2例死亡 - 0.92%);未建立人工气道的药物治疗 = 214例(13例死亡 - 6.1%)。气管切开术或鼻气管插管在发病率和死亡率上的差异非常小,以至于选择应由当地因素决定。儿童不应采用未建立人工气道的药物治疗。